CDMO
Peev Xwm R & D- Tshwj Xeeb
Chiral synthesis (Kev daws teeb meem thiab Asymmetric synthesis, Catalyst thiab Enzyme)
Xaiv kev hloov pauv ntawm enantiomers (Hloov pauv tsis muaj teeb meem rau kev teeb tsa siv tau)
Kev Txhim Kho Txheej Txheem Tsis Raug Cai
Kev qhia kom tsis huv (TOF, GC-MS, LC-MS, NMR)
Mutagenic impurity tshawb fawb
Kev tshawb fawb Elemental Impurity (ICP-MS)
Cov Tshuaj Tshwj Xeeb
Hydrazines, 1500L/pawg
Suzuki Coupling, 100L/pawg
Fischer-Indole Synthesis, 2000L/pawg
Ullmann (Cu lossis Pd catalysis) Kev sib txuas, 500L/pawg
Vilsmeier Reaction, 500L/pawg
Kev Ntsuas Siab Siab:
* hydrogenation & hydroformylation: 1-2000L
Qhov ntsuas kub tsawg heev: (-80 ℃) 500L ~ 5000L/pawg
Organometallic reagents:
* Alkyl lithium, 1500L/pawg, ntau zaus (methyl lithium, n-butyl lithium, phenyl lithium)
* Grignard Reagent, 1500L/pawg
Peev Xwm Ntau Lawm
Tsawg kawg 20-35 GMP cov kab ntau lawm (nrog 10 HVAC system)
Tsawg kawg 350-500 Reactors (Tag Nrho: 350,000L-1000,000L)
Cov Khoom Siv Tau Zoo
Kub: Los ntawm -100 ℃ txog 200 ℃
Siab: Los ntawm 50 Pa mus rau 35 atm
Cov ntaub ntawv ntawm Reactors: iav-kab, Stainless hlau, Halar Coated.
Reactors Loj: Ntawm 10L txog 8000L
